Introduction : Artificial Insemination remains to be a simple and relatively inexpensive exhaustible form of assisted reproductive technique. Sperm sources used for artificial insemination may be from the husband/autologous sperms(AIA) and donor/heterologous sperms (AID) The study involves the mixing of husband and donor sperms (AIM) for artificial insemination. Method: Couples with oligospermic male (total sperm count <10 million) after failed treatment of primary artificial insemination using autologous/husband as donors(A.I.A.) were included into the study. After failure of treatment with 2 - 3 cycles, the option of artificial insemination with donor/heterologous sperms (A.I.D.) or artificial insemination with mixed husband and donor sperms(A.I.M.) was presented to the couples. Sperm composition for artificial insemination with mixed husband and donor sperms was made using 1/3 volume from the husband and 2/3 volume from the donor. Results: Results of study show a total of 555 couples undergoing A.I.M. There was 87% pregnancy rate and 67% baby rate. A.I.M.produced pregnancy rates higher compared to A.I.D. and A.I.A. artificial insemination groups. Of the cases of artificial insemination with mixed donor and husband sperms which produced pregnancy and subsequent live birth, 13 couples came back with results of HLA typing of the child and oligospermic father. Paternity of the offspring was confirmed to be the father in 10 out of the 13 cases. Conclusion: Artificial insemination using mixed husband and donor sperms produced a higher pregnancy rate (87%) compared to artificial insemination using pure donor sperms (AID) and autologous insemination of oligospermic males.
Conflict of Interest: None disclosed
Financial Support/Funding: None disclosed
Recorded: Sydney, Australia, April 2007
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